Ten-year review of Clostridium difficile infection in acute care hospitals in the USA, 2005-2014

Clostridium difficile infection (CDI) is a major health concern for acute care hospitals because of the increase in the number and severity of cases. Using the Nationwide Inpatient Sample database, a 10-year review was performed on the trends in incidence, mortality, and hospital charges for CDI patients in acute care hospitals during 2005-2014. The review found increased CDI incidence and hospital charges, but decreased mortality during the 10-year study period.