Pneumopathies non infectieuses induites par les biothérapies ciblées

The use of biologics has shown strong clinical benefits in patients with rheumatic diseases. Biologics-induced lung disease may manifest as variable clinical radiological patterns, including interstitial lung diseases, sarcoid-like or auto-immune manifestations. Although some risk factors have been identified, the precise mechanisms of biologics-induced infiltrative lung disease are largely unknown. Drug causality should be carefully evaluated and infectious diseases ruled out.