کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8752293 | 1594450 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Gorham-Stout disease or new entity on the basis of vasculopathy
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پزشکی و دندانپزشکی (عمومی)
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Gorham-Stout disease (GSD) is a rare osteolytic bone disease also known as vanishing bone disease. The pathogenesis of GSD is not well understood. Studies showed that lymphatic and blood endothelial cells in addition to macrophages secrete TNFα and IL-6 that stimulate osteoclast formation with osteolysis. Also TNFα secretion inhibits osteoblast differentiation and new bone formation. It is known that cytokines such as TNFα, IL-1 and complement system activation are responsible for inflammation and necrosis in the vessel wall at vasculitis. Both diseases have similar pathogenesis. Here, we presented a case of Gorham's disease with involvement of bilateral humerus, systemic arterial thrombosis and mesenteric vasculitis.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Alexandria Journal of Medicine - Volume 53, Issue 2, June 2017, Pages 193-196
Journal: Alexandria Journal of Medicine - Volume 53, Issue 2, June 2017, Pages 193-196
نویسندگان
H. Hasan Yeter,