کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8770046 | 1598219 | 2017 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report
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کلمات کلیدی
Kidney Disease Outcomes Quality Initiative (KDOQI)Chronic kidney disease (CKD) - بیماری مزمن کلیه (CKD)end-stage renal disease (ESRD) - بیماری کلیوی مرحله پایانی (ESRD)Transient ischemic attack (TIA) - حمله ایسکمیک گذرا (TIA)Hemorrhage - خونریزیBleeding - خونریزیDialysis - دیالیزPeritoneal dialysis - دیالیز صفاقیStroke - سکته مغزیOral anticoagulants - ضد انعقاد خوراکیAtrial fibrillation (AF) - فیبریلاسیون دهلیزی (AF)Kidney failure - نارسایی کلیهHemodialysis - همودیالیزWarfarin - وارفارین
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیماریهای کلیوی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report Oral Anticoagulants to Prevent Stroke in Nonvalvular Atrial Fibrillation in Patients With CKD Stage 5D: An NKF-KDOQI Controversies Report](/preview/png/8770046.png)
چکیده انگلیسی
Stroke risk may be more than 3-fold higher among patients with chronic kidney disease stage 5D (CKD-5D) compared to the general population, with the highest stroke rates noted among those 85 years and older. Atrial fibrillation (AF), a strong risk factor for stroke, is the most common arrhythmia and affects >7% of the population with CKD-5D. Warfarin use is widely acknowledged as an important intervention for stroke prevention with nonvalvular AF in the general population. However, use of oral anticoagulants for stroke prevention in patients with CKD-5D and nonvalvular AF continues to be debated by the nephrology community. In this National Kidney Foundation-Kidney Disease Outcomes Quality Initiative (NKF-KDOQI) controversies report, we discuss the existing observational studies that examine warfarin use and associated stroke and bleeding risks in adults with CKD-5D and AF. Non-vitamin K-dependent oral anticoagulants and their potential use for stroke prevention in patients with CKD-5D and nonvalvular AF are also discussed. Data from randomized clinical trials are urgently needed to determine the benefits and risks of oral anticoagulant use for stroke prevention in the setting of AF among patients with CKD-5D.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: American Journal of Kidney Diseases - Volume 70, Issue 6, December 2017, Pages 859-868
Journal: American Journal of Kidney Diseases - Volume 70, Issue 6, December 2017, Pages 859-868
نویسندگان
Vinod K. MD, Charles A. MD, Mark J. MD, MS, Michael J. MD, Ravindra MD, Bernard G. MD, MPH, Michael V. MD, Holly MD, MPH,