کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8783281 | 1600751 | 2017 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Lack of beneficial effect of activated charcoal in lead induced testicular toxicity in male albino rats
ترجمه فارسی عنوان
عدم اثربخشی فعالیت زغال چوب فعال در سمیت بیضه ناشی از سرب در موش صحرایی نر آلبینو
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کلمات کلیدی
سمیت مزمن سرب زغال چوب فعال خسارت مفاصل، بیومارکرها و بهداشت عمومی،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
چکیده انگلیسی
Objective: Lead is a multi-organ toxicant implicated in various diseases including testicular toxicity. In search of cheap and readily available antidote this study has investigated a beneficial role of activated charcoal in lead induced testicular toxicity in male albino rats. Materials and Method: Eighteen male albino rats were divided into three groups of six rats per group. Group 1 (control rats) received deionised water (10Â ml/kg), group 2 was given lead acetate solution 60Â mg/kg and group 3 rats were given lead acetate (60Â mg/kg) followed by Activated charcoal, AC (1000Â mg/kg) by oral gavage daily for 28Â days. Absolute and relative weights of testis, epididymal sperm reserve, testicular sperm count, percent sperm motility and percent sperm viability were monitored. Results: AC failed to show any significant beneficial effect in ameliorating lead induced testicular toxicity. Conclusions: There seem to be a poor adsorption on lead onto AC in vivo.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Middle East Fertility Society Journal - Volume 22, Issue 3, September 2017, Pages 189-192
Journal: Middle East Fertility Society Journal - Volume 22, Issue 3, September 2017, Pages 189-192
نویسندگان
Samuel James Offor, Herbert Orji Chinedu Mbagwu, Orish Ebere Orisakwe,