کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
878424 1471161 2015 15 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Study progression MRI findings with pathologic correlation in hepatitis B virus-associated multistage hepatocellular carcinoma
موضوعات مرتبط
مهندسی و علوم پایه سایر رشته های مهندسی مهندسی پزشکی
پیش نمایش صفحه اول مقاله
Study progression MRI findings with pathologic correlation in hepatitis B virus-associated multistage hepatocellular carcinoma
چکیده انگلیسی

Hepatocellular carcinoma (HCC) is one of the most common malignancies worldwide. It is recognized that the vast majority of HCC (90%) develops in a hepatitis/cirrhotic setting, of which the early detection is very important. Pathologically, HCC develops in a multistage fashion in the following steps: from regenerative nodules (RNs), low-grade dysplastic nodules (LGDNs), high-grade dysplastic nodules (HGDNs, the premalignant phase, borderline lesions), nodule-in-nodule HCC, early small HCCs (eHCC, the early carcinoma phase, well-differentiated), progressed small HCCs (pHCC, well to moderately-differentiated), and large HCCs (moderately to poorly-differentiated, so-called classical HCC). Characterization of cirrhotic nodules on the basis of imaging and pathologic findings is complicated by an overlap in findings associated with each type of nodule, a reflection of their multistep transitions. Recent progress in imaging modality, especially MRI, is starting to play a crucial role in the evaluation of hepatocarcinogenesis, which facilitates detection and characterization in most cases of cirrhotic nodules. In this review paper, we go over and detailedly illustrate the pathological features and MR imaging findings of these nodular lesions, and enable to understand these nodules more completely, so as to accurately diagnose cirrhotic nodules.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Radiology of Infectious Diseases - Volume 2, Issue 2, September 2015, Pages 94–108
نویسندگان
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