کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8809544 | 1606990 | 2018 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antidepressant-Induced Activation in Children and Adolescents: Risk, Recognition and Management
ترجمه فارسی عنوان
فعال سازی ناشی از ضد افسردگی در کودکان و نوجوانان: خطر، تشخیص و مدیریت
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موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی
The tolerability of antidepressants is poorly characterized in children and adolescents with depressive and anxiety disorders. Among adverse events that affect the tolerability of antidepressants in youth is activation, a cluster of symptoms that represent a hyperarousal event characterized by impulsivity, restlessness, and/or insomnia. This cluster of symptoms was first identified as a side effect of selective serotonin and selective serotonin norepinephrine inhibitors (SSRIs and SSNRIs) in the early 1990s; however, activation remains poorly characterized in terms of prevalence, risk factors, and pathophysiology. This article describes the pathophysiology of antidepressant-related activation, predictors of activation and its clinical management in youth with depressive and anxiety disorders who are treated with antidepressant medications.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Problems in Pediatric and Adolescent Health Care - Volume 48, Issue 2, February 2018, Pages 50-62
Journal: Current Problems in Pediatric and Adolescent Health Care - Volume 48, Issue 2, February 2018, Pages 50-62
نویسندگان
Marissa J. BS, Martine MD, PhD, Melissa P. MD, MS, Robert K. PhD, Jeffrey R. MD,