کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8811956 1607134 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Frequency of gonadal tumours in complete androgen insensitivity syndrome (CAIS): A retrospective case-series analysis
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
پیش نمایش صفحه اول مقاله
Frequency of gonadal tumours in complete androgen insensitivity syndrome (CAIS): A retrospective case-series analysis
چکیده انگلیسی
The results support the current recommendation that gonads in CAIS can be retained until early adulthood. The small number of individuals with gonadectomy after age 20 years do not allow firm conclusion regarding later adulthood. Therefore, it is recommended that the option of gonadectomy be discussed in adulthood. Some form of regular surveillance of the gonads is then recommended, although none of the available options are ideal.Summary table. Abnormal histology.Benign tumourn = 6 Sertoli cell adenoma (SCA)n = 8 testicular hamartoma (TH)n = 2 mixed SCA + THGerm cell neoplasia in situ (GCNIS) (age at gonadectomy)n = 6 (2 years 9 months, 16 years, 17 years,*17 years, 20 years,*53 years)*Associated with benign changesMalignant tumour (age at gonadectomy)n = 1 malignant sex cord stromal tumour (68 years)n = 1 seminoma (30 years)
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Urology - Volume 13, Issue 5, October 2017, Pages 498.e1-498.e6
نویسندگان
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