Polypharmacy, chronic kidney disease, and benign prostatic hyperplasia in patients with chronic obstructive pulmonary disease newly treated with long-acting anticholinergics

- The prevalence of polypharmacy, CKD and, in men, BPH increases with age.
- Polypharmacy is highly prevalent across all age in COPD patients initiating a LAAC.
- Polypharmacy, CKD, and BPH significantly increase the incidence of AUR.
- Physicians should monitor AUR following initiation of a LAAC among COPD patients.