کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8826443 1610618 2017 10 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Estado actual del tratamiento de la axila en la cirugía primaria del cáncer de mama: Revisión sistemática de su impacto en la supervivencia
ترجمه فارسی عنوان
وضعیت فعلی درمان زیر بغل در جراحی سرطان پستان اولیه: بررسی سیستماتیک اثر آن بر بقای
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
چکیده انگلیسی
Sentinel lymph node biopsy and ACOSOG-Z0011 criteria have modified axillary treatment in breast cancer surgery. We performed a systematic review of studies assessing the impact of axillary treatment on survival. The search showed 6891 potentially eligible items. Of them, 23 clinical trials and 12 meta-analyses published between 1980 and 2017 met the study criteria. The review revealed that axillary lymph node dissection (ALND) can be omitted in patients pN0 and pN1mic, without compromising survival. In patients pN1 it is proposed not to treat the axilla or replace ALND for axillary radiotherapy. The main limitations of this study are the inclusion of old tests that do not use therapeutic targets and lack of risk categorization of relapse. In conclusion, axillary treatment can be avoided in patients without metastatic involvement or micrometastases in the sentinel lymph node. However, there is no evidence to make a recommendation of axillary treatment in N1 patients, so individualized analysis of patient risk factors is needed.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Cirugía Española - Volume 95, Issue 9, November 2017, Pages 503-512
نویسندگان
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