کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8839681 | 1613748 | 2018 | 52 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fasting or systemic des-acyl ghrelin administration to rats facilitates thermoregulatory behavior in a cold environment
ترجمه فارسی عنوان
مصرف روزانه و یا سیستمیک تجویز نیکل گریلین به موش ها رفتارهای گرماسنجی در محیط سرد را تسهیل می کند
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کلمات کلیدی
Celcentral amygdaloid nucleus, lateral divisionbasomedial amygdaloid nucleuscentral amygdaloid nucleus, medial divisionMePVbasolateral amygdaloid nucleus, posterior partdes-acyl ghrelinLPBBLVcFosACOAIPCEMBLABMACECMEADMPO - DFOBody temperature - دمای بدنTail skin temperature - دمای پوست دمFasting - روزه داریGranular insular cortex - قشر ساقه غدهSecondary somatosensory cortex - قشر کمخونی ثانویهBMP - مدیریت فرایند کسب و کارmedial preoptic area - منطقه پیشوپتیک مدیاanterior cortical amygdaloid nucleus - هسته آمیگدالید قشر قشر قدامیbasolateral amygdaloid nucleus - هسته آمیگدولئید basolateralParastrial nucleus - هسته عادیcentral amygdaloid nucleus - هسته مرکزی amygdaloidmedial amygdaloid nucleus - هسته مرکزی آمیگدولیدbasolateral amygdaloid nucleus, anterior part - هسته مینا دهلیزی، قسمت قدامی قدامیlateral parabrachial nucleus - هسته پاراباژیال جانبی جانبی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
چکیده انگلیسی
Fasted rats place their tails underneath their body trunks in the cold (tail-hiding behavior), which is a thermoregulatory behavior. The aim of the present study was to investigate the effect of fasting and des-acyl ghrelin, a hormone related to fasting, on tail-hiding behavior and neural activity in the cold. Wistar rats were divided into 'fed', '42-h fasting' and des-acyl ghrelin groups. The rats received an intraperitoneal saline or 30-μg des-acyl ghrelin injection, and were then exposed to 27â¯Â°C or 15â¯Â°C for 2-h with continuous body temperature (Tb), tail skin temperature (Ttail), and tail-hiding behavior measurements. cFos immunoreactive (cFos-IR) cells in the insula, secondary somatosensory cortex, medial preoptic nucleus, parastrial nucleus, amygdala, and lateral parabrachial nucleus were counted in four segments: seg1, 2, 3, and 4 (bregma â0.36, â1.44, â2.64, and â9.00â¯mm), respectively. At 15â¯Â°C, Tb and Ttail were lower in the 42-h fasting group than in the fed and des-acyl ghrelin groups, and the duration of tail-hiding behavior was longer in the 42-h fasting and des-acyl ghrelin groups than in the fed group. The onset of tail-hiding behavior more advanced in the des-acyl ghrelin group than in the fed group at 15â¯Â°C. Only at the insula in seg3 at 15â¯Â°C, the number of cFos-IR cells was greater in the 42-h fasting group than in the fed group. Both the 42-h fasting and des-acyl ghrelin groups might modulate the tail-hiding behavior of rats in a cold, and a part of the insula might be involved this response during fasting.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research - Volume 1696, 1 October 2018, Pages 10-21
Journal: Brain Research - Volume 1696, 1 October 2018, Pages 10-21
نویسندگان
Yuki Uchida, Kei Nagashima, Kazunari Yuri,