Generic flow sheet model for early inventory estimates of industrial microbial processes. I. Flowsheet development, microbial growth and product formation

For many bioprocess systems, the desired material and energy balance input data are not available at an early stage of process design. A model (CeBER Bioprocess Modeller) was developed to provide these material and energy balance data, allowing for aerobic or anaerobic, intra- or extracellular product formation or biomass growth, in a continuous or batch process for various bioproducts. This paper explains the model development, up to the product formation/biomass growth stages.88