The expression and significance of IL-6 and IL-10 in the process of clinical common bacteria bloodstream infection in the mouse models analyzed by the Luminex® xMAP™ System

There were significantly increases of the serum IL-6 and IL-10 at the early stage of 4 different bacterial BSIs. The increase degrees and rates of IL-6 and IL-10 in E. coli and K. pneumoniae groups were significantly higher than those in S. aureus group and E. faecalis group. The combination of IL-6 and IL-10 could be used in the early diagnosis for bacterial BSI and may provide a basis for clinical therapy.