Vascular profile of patient with familial hypercholesterolemia

Familial Hypercholesterolaemia is a common genetic cause of premature Coronary heart Disease (CHD). It is an autosomal, dominant, inherited disorder of lipoprotein metabolism that results in a raised Low Density Lipoprotein Cholesterol (LDL-C) plasma concentration. The current study presented a 36 year old female having angina on exertion class 2 for past 1 year. She had large xanthomas over dorsal aspect of both the hands and feet and xanthelasma over eyelid. She was diagnosed as case of familial hypercholesterolemia. Her vascular profile revealed aortic root calcification, left main with triple vessel disease, right common carotid artery stenosis and atherosclerotic narrowing of aorta distal to left subclavian artery.