کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8930113 | 1644513 | 2017 | 15 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Perioperative management of rare coagulation factor deficiency states in cardiac surgery
ترجمه فارسی عنوان
مدیریت مجدد فاکتورهای کمبود فاکتور انعقادی نادر در جراحی قلب
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کلمات کلیدی
عوامل انعقادی خون، تزریق خون، کلاژن ها، جراحی قفسه سینه،
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
بیهوشی و پزشکی درد
چکیده انگلیسی
Rare bleeding disorders (RBDs) include the hereditary deficiency of fibrinogen, factor (F)II, FV, FVâ+âFVIII, FVII, FX, FXI or FXIII. RBDs do not confer a protective effect against atheromatous plaque formation, and thus the need for cardiovascular (CV) surgery in RBD patients is expected to increase with improved healthcare access (diagnosis and management) and longevity of the population. Clinical data regarding the management of RBDs in this setting are sparse, but the perioperative care team is obliged to gain a better understanding on available biological and pharmacological hemostatic agents. Perioperative management of RBDs in CV surgery is further complicated by heparin anticoagulation, haemodilution, and consumption of procoagulant and anticoagulant proteins associated with cardiopulmonary bypass (CPB). The aims of this review are to summarize pathophysiology of RBDs and laboratory monitoring pertinent to CV surgery, available factor replacement agents, and to provide the framework for perioperative coagulation management of RBD patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: British Journal of Anaesthesia - Volume 119, Issue 3, September 2017, Pages 354-368
Journal: British Journal of Anaesthesia - Volume 119, Issue 3, September 2017, Pages 354-368
نویسندگان
E.R. Strauss, M.A. Mazzeffi, B. Williams, N.S. Key, K.A. Tanaka,