Analgesia with sevoflurane during labour: II. Sevoflurane compared with Entonox for labour analgesia†‡

We conclude that self-administered sevoflurane at subanaesthetic concentration (0.8%) can provide useful pain relief during the first stage of labour, and to a greater extent than Entonox. Although greater sedative effects were experienced with sevoflurane, it was preferred to Entonox.