کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8946035 1645316 2018 43 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Towards an objective test of chronic tinnitus: Properties of auditory cortical potentials evoked by silent gaps in tinnitus-like sounds
ترجمه فارسی عنوان
به سوی یک آزمون عینی از وزوز گوش مزمن: ویژگی های پتانسیل قوز شنیداری ناشی از شکاف ساکت در صداهای وزوز گوش
کلمات کلیدی
وزوز گوش، تشخیص فاصله، شنوایی موجب بروز پتانسیل می شود، قدرت میدان جهانی،
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی سیستم های حسی
چکیده انگلیسی
A common method designed to identify if an animal hears tinnitus assumes that tinnitus “fills-in” silent gaps in background sound. This phenomenon has not been reliably demonstrated in humans. One test of the gap-filling hypothesis would be to determine if gap-evoked cortical potentials are absent or attenuated when measured within background sound matched to the tinnitus sensation. However the tinnitus sensation is usually of low intensity and of high frequency, and it is unknown if cortical responses can be measured with such “weak” stimulus properties. Therefore the aim of the present study was to test the plausibility of observing these responses in the EEG in humans without tinnitus. Twelve non-tinnitus participants heard narrowband noises centered at sound frequencies of 5 or 10 kHz at sensation levels of either 5, 15, or 30 dB. Silent gaps of 20 ms duration were randomly inserted into noise stimuli, and cortical potentials evoked by these gaps were measured by 64-channel EEG. Gap-evoked cortical responses were statistically identifiable in all conditions for all but one participant. Responses were not significantly different between noise frequencies or levels. Results suggest that cortical responses can be measured when evoked by gaps in sounds that mirror acoustic properties of tinnitus. This design can validate the animal model and be used as a tinnitus diagnosis test in humans.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Hearing Research - Volume 366, September 2018, Pages 90-98
نویسندگان
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