کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8958595 | 1646268 | 2018 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Small-colony variant of Staphylococcus lugdunensis in prosthetic joint infection
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
ارتوپدی، پزشکی ورزشی و توانبخشی
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چکیده انگلیسی
Prosthetic joint infection is usually caused by staphylococci. Among the coagulase-negative staphylococci, Staphylococcus lugdunensis is important because it behaves as a pathogen similar to S aureus. It also develops biofilms, and the biofilm phenotype can appear as small-colony variants. Although genetically indistinguishable, they differ in size and antibiotic susceptibility from the parent strain and are responsible for chronic persistent infection and failure of antibiotic treatment. They can also lead to misinterpretation of results. The patient reported here underwent total knee replacement and 2 years later presented with prosthetic joint infection. Tissue samples and prosthesis taken at revision grew S lugdunensis, the majority of which were small-colony variants. Recommendations are made for their detection and identification.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Arthroplasty Today - Volume 4, Issue 3, September 2018, Pages 257-260
Journal: Arthroplasty Today - Volume 4, Issue 3, September 2018, Pages 257-260
نویسندگان
Mohamed PhD, MRCS, Benjamin PhD, FRCS Orth, Roger PhD, FRCPath,