کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
899237 915368 2011 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cautions and warnings on the US OTC label for nicotine replacement: What's a doctor to do?
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
Cautions and warnings on the US OTC label for nicotine replacement: What's a doctor to do?
چکیده انگلیسی

BackgroundFDA-approved labeling for over-the-counter (OTC) nicotine replacement therapy (NRT) limits duration of use to a relatively short period of time (10–12 weeks) and explicitly advises against NRT use while smoking or with additional forms of NRT.ObjectiveTo consider and summarize evidence accumulated since the OTC label was created regarding the safety and efficacy of longer-term and concomitant use to provide recommendations regarding these uses.MethodLiterature searches were conducted on Medline, journal websites, and Internet search engines, with findings reviewed by six smoking cessation researchers.ResultsPersistent (i.e., long-term) use of NRT does not appear harmful and self-selected persistent use is primarily driven by concerns about relapse to smoking, not addiction. Similarly, continued use of NRT and tobacco during a lapse or relapse and combination NRT treatment do not appear harmful and appear to enhance efficacy.ConclusionsPersistent users of NRT should be counseled to reduce and stop NRT only when they are not concerned about relapsing to smoking. Use of NRT with return to smoking during a lapse or relapse should not be automatically discontinued. Combination NRT therapy should be considered for all smokers, especially those who are unable to quit smoking using a single form of NRT.

Research Highlights
► Persistent users should stop NRT only when not concerned about relapse to smoking.
► NRT should not be automatically discontinued during a lapse or relapse to smoking.
► Combination NRT therapy should be considered for all smokers.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Addictive Behaviors - Volume 36, Issue 4, April 2011, Pages 327–332
نویسندگان
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