کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8999847 | 1116229 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Effect of the aqueous extract of Hyptis pectinata on liver mitochondrial respiration
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
بیوشیمی بالینی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Effect of the aqueous extract of Hyptis pectinata on liver mitochondrial respiration Effect of the aqueous extract of Hyptis pectinata on liver mitochondrial respiration](/preview/png/8999847.png)
چکیده انگلیسی
Some studies have indicated that mitochondria may be the target organelle of plants. We therefore decided to assess the effects of the aqueous extract of Hyptis pectinata leaves on liver mitochondrial respiratory function in vitro. Eight rat livers were subjected to isolation of mitochondria by differential centrifugation. In an adequate medium, the plant extract was added at different concentrations. The analyzed data were: state 3, state 4 and respiratory control ratio (RCR). H. pectinata extract caused a statistically significant decrease in state 3 (at 0.05, 0.1 and 0.2Â mg/mg protein) and RCR (at 0.05, 0.1 and 0.2Â mg/mg protein). Respiratory state 4 was not altered by the increasing concentrations. In conclusion, the aqueous extract of H. pectinata leaves may not injure the mitochondrial inner membrane but decreases significantly the oxidative phosphorylation.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Phytomedicine - Volume 12, Issue 5, 16 May 2005, Pages 359-362
Journal: Phytomedicine - Volume 12, Issue 5, 16 May 2005, Pages 359-362
نویسندگان
G.B. Melo, R.L. Silva, V.A. Melo, Ã.R. Antoniolli, M.E. Jordani Souza, M.C. Jordani, O. Jr.,