کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9030212 | 1130726 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Antioxidant responses in Meretrix meretrix exposed to environmentally relevant doses of tributyltin
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم محیط زیست
بهداشت، سم شناسی و جهش زایی
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چکیده انگلیسی
The effects on reduced glutathione (GSH) levels, glutathione-S-transferases (GST) and glutathione peroxidase (GPx) activities of digestive gland in Meretrix meretrix exposed to tributyltin (TBT) at environmental levels (0.1, 1, 10Â ng/L as Sn), in experimental condition, were evaluated. The GST activities in 0.1Â ng/L groups were significantly elevated after exposure for 2 days, and were significantly inhibited after exposure to 10Â ng/L TBT for 8 and 20 days. The GPx activities were mainly induced by TBT exposure, except the GPx activities in 10Â ng/L groups were significantly inhibited after exposure for 2 days. The GSH content was significantly decreased with prolonged exposure. The GSH content, GST and GPx activities in all exposure groups, transferred to clean recovery tanks for 20 days, were recovered to the level corresponding to that of the control group. Taken together, our present studies indicate that exposure to TBT may induce strong production of reactive oxygen species in the clams.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Toxicology and Pharmacology - Volume 20, Issue 1, July 2005, Pages 107-111
Journal: Environmental Toxicology and Pharmacology - Volume 20, Issue 1, July 2005, Pages 107-111
نویسندگان
Zhouying Huang, Yixin Chen, Yang Zhao, Zhenghong Zuo, Mei Chen, Chonggang Wang,