کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9035020 1562445 2005 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Vitamins deficiency in developing chick during chromium intoxication and protection thereof
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست بهداشت، سم شناسی و جهش زایی
پیش نمایش صفحه اول مقاله
Vitamins deficiency in developing chick during chromium intoxication and protection thereof
چکیده انگلیسی
Deficiency of various vitamins in postnatally developing chick during chromium intoxication and their recovery during vitamins (B and E) and glutathione therapies has been investigated. Study was concentrated on liver, kidney, muscles and serum. Newly hatched chicks were reared in laboratory. They were treated with a daily dose of 10 mg/kg/day potassium dichromate from 2nd to 8th day of their age. Thereafter, one group was sacrificed on 9th day. Second group was kept without intoxication for another 7 days and sacrificed on 16th day. Three groups of chromium pretoxicated animals were exposed to therapeutic agents like vitamins (B and E) and glutathione for another 7 days. These animals were sacrificed on 16th day of their age along with control. Study showed chromium intoxication decreases vitamins (B1, B2, B6 and E) in all the tissues and serum. The maximum decrease was recorded in serum. The 7 days pretoxicated animals kept without any treatment for 7 days revealed a slow increase of vitamins with few exceptions. Nevertheless, the recovery of vitamins was quick and significant during vitamins and glutathione therapy and in some cases control level was achieved.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Toxicology - Volume 211, Issues 1–2, 1 July 2005, Pages 124-131
نویسندگان
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