کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
909351 917277 2014 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Genetic and environmental causes of variation in adolescent anxiety symptoms: A multiple-rater twin study
ترجمه فارسی عنوان
علل ژنتیکی و محیطی تغییرات در علائم اضطراب نوجوانان: مطالعه دوقلوهای چندگانه
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی


• Variation in adolescent anxiety symptoms is mainly genetically determined.
• The heritability of adolescent anxiety seems to be higher for girls than for boys.
• It is important to involve multiple informants for the study of adolescent anxiety.

Heritability estimates for adolescent anxiety vary across studies, partly depending on who is rating the symptoms. The goal of our study was to estimate genetic and environmental influences using a multi-informant design with responses from a population-based sample of adolescent twins, their mothers and their fathers (N = 1394 families).Results from multivariate biometrical modeling indicated quantitative, but no qualitative sex differences in etiology. The best fitting model was an AE Common Pathway model, defining anxiety as a latent factor common to all informants. This model offers error free estimates of genetic and environmental influences explaining the latent factor variance.Variation in the latent factor was highly genetic, with heritability estimates of 65% for boys and 74% for girls. Non-shared environmental effects explained the remaining variance. In addition, there were significant rater-specific genetic and environmental effects for both sexes.The observed rater differences underline the importance of using several informants when studying adolescent anxiety.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Anxiety Disorders - Volume 28, Issue 4, May 2014, Pages 363–371
نویسندگان
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