Antiphospholipid Antibodies as a Cause of Pulmonary Capillaritis and Diffuse Alveolar Hemorrhage: A Case Series and Literature Review

The syndrome of DAH and pulmonary capillaritis is further defined. Evidence supports a causative relationship between PAPS, pulmonary capillaritis, and DAH in the absence of thromboembolic disease. Further elucidation of a possible nonthrombotic mechanism of antiphospholipid antibody-mediated pathology is needed to guide future therapies for this unusual manifestation of PAPS.