کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9122172 | 1159205 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Role of Escherichia coli DnaK and DnaJ chaperones in spontaneous and induced mutagenesis and their effect on UmuC stability
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
ژنتیک
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Role of Escherichia coli DnaK and DnaJ chaperones in spontaneous and induced mutagenesis and their effect on UmuC stability Role of Escherichia coli DnaK and DnaJ chaperones in spontaneous and induced mutagenesis and their effect on UmuC stability](/preview/png/9122172.png)
چکیده انگلیسی
The frequency of spontaneous as well as induced reversions of auxotrophic mutations in Escherichia coli AB1157 and its ÎdnaK and ÎdnaKdnaJ derivatives was estimated. The obtained results demonstrate that both mutants tested are characterized by elevated frequency of spontaneous reversions compared to their AB1157 parent. In contrast, the frequency of reversions induced by UV and MMS, i.e. agents inducing the SOS response, is reduced in ÎdnaJ and ÎdnaKdnaJ mutants, pointing to the possible defect of these mutants in error prone repair. Due to the fact that UmuC protein is one of the main players executing the error prone repair, its stability in ÎdnaJ and ÎdnaKdnaJ mutants was also studied. Reduced UmuC stability was demonstrated only in the ÎdnaKdnaJ mutant.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: FEMS Microbiology Letters - Volume 242, Issue 2, 15 January 2005, Pages 361-366
Journal: FEMS Microbiology Letters - Volume 242, Issue 2, 15 January 2005, Pages 361-366
نویسندگان
Anna M. Grudniak, Mariusz KuÄ, Krystyna I. Wolska,