کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9166818 1174230 2005 42 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Molecular Mechanisms of Myocardial Infarction
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Molecular Mechanisms of Myocardial Infarction
چکیده انگلیسی
Despite an increased knowledge of risk factors for atherosclerotic heart disease, it remains nearly endemic in Western society. Despite the high penetrance, only a fraction of those with the disease progress to develop a frank myocardial infarction (MI). Over the past decade, it has become clear that inflammation plays an important role in the pathogenesis of MI. Inflammatory arterial disease therefore may be a better term for the subset of patients that develop the serious adverse consequences related to the rupture of the intracoronary plaque. Using newer molecular techniques such as high-throughput SNP analysis, genome-wide scanning, and enriched pedigree analysis, many of the specific mechanisms underlying the inflammatory milieu involved in this transition have been elucidated and may help identify those at risk for the adverse events associated with atherosclerotic disease.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Problems in Cardiology - Volume 30, Issue 7, July 2005, Pages 333-374
نویسندگان
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