کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9171719 1178922 2005 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Discovery of gradient pattern in dominant frequency maps during fibrillation: implication of rotor drift and epicardial conduction velocity changes
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
Discovery of gradient pattern in dominant frequency maps during fibrillation: implication of rotor drift and epicardial conduction velocity changes
چکیده انگلیسی
Dominant frequency (DF) maps for mapping epicardial activations of ventricular fibrillation (VF) have been studied mainly using fast Fourier transform (FFT). Small and discrete DF domains exhibited in these DF maps have undermined the hypothesis of mother rotor for VF maintenance. We applied continuous Fourier transform (CFT) to generate high-precision DF maps and studied characteristics of these high-precision DF maps. Optical epicardial activations were recorded in isolated rabbit hearts (n = 10). Continuous Fourier transform of 1-second segments was performed in VF (n = 188) and ventricular tachycardia (n = 189) at 0.1 Hz precisions. Banded gradient patterns of gradual change in DF values were observed in 136 of 188 VF segments, but not in ventricular tachycardia. These gradients were not observed when FFT was used. Gradients were observed along the conduction path of reentrant-like waves with decreasing DF values along the path. Spectra in the gradients did not exhibit bimodal spectra as is usually observed in traditional DF domain boundaries. Time-space plots revealed clear association between gradient pattern and epicardial conduction velocity changes. Prior simulation studies predicted a gradient in activation rate during rotor drift. This gradient pattern has been observed for the first time experimentally by only using CFT, but not FFT. High-precision DF videos indicated the existence of gradient movement from one spatial location to another, smoothly instead of randomly disappearing from one location and appearing in another. The discovery of associated pseudoconduction velocity changes, and gradient patterns might suggest that dominant rotor (mother rotor) drifting plays a maintenance role only detectable by CFT and not FFT.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Electrocardiology - Volume 38, Issue 4, Supplement, October 2005, Pages 159-165
نویسندگان
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