کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9197903 1188879 2005 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Temporal evolution of the CBV-fMRI signal to rat whisker stimulation of variable duration and intensity: A linearity analysis
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Temporal evolution of the CBV-fMRI signal to rat whisker stimulation of variable duration and intensity: A linearity analysis
چکیده انگلیسی
Cerebral blood volume functional magnetic resonance imaging (CBV-fMRI) experiments employing iron oxide contrast agent were conducted in rat whisker barrel cortex at 3 Tesla. Stimuli of constant frequency (12 Hz) but variable duration and intensity were delivered separately using a homemade whisker stimulator. The temporal behavior of CBV-fMRI signals was investigated using a linearity analysis method. Both superposition and scaling tests show that CBV-fMRI responses are generally consistent with a linear time-invariant (LTI) model. In particular, the response to a stimulus of higher intensity can be linearly scaled from that of lower intensity. However, significant deviations exist when the stimulus duration is manipulated, particularly in the trailing edge of the CBV-fMRI response curves.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 26, Issue 2, June 2005, Pages 432-440
نویسندگان
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