کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
9198114 1188888 2005 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cortical thickness analysis examined through power analysis and a population simulation
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب شناختی
پیش نمایش صفحه اول مقاله
Cortical thickness analysis examined through power analysis and a population simulation
چکیده انگلیسی
The precision of cortical thickness measurements was studied using a simulated population study and single subject reproducibility metrics. Cortical thickness was shown to be a reliable method, reaching a sensitivity (probability of a true-positive) of 0.93. Six different cortical thickness metrics were compared. The simplest and most precise method measures the distance between corresponding vertices from the white matter to the gray matter surface. Given two groups of 25 subjects, a 0.6-mm (15%) change in thickness can be recovered after blurring with a 3-D Gaussian kernel (full-width half max = 30 mm). Smoothing across the 2-D surface manifold also improves precision; in this experiment, the optimal kernel size was 30 mm.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: NeuroImage - Volume 24, Issue 1, 1 January 2005, Pages 163-173
نویسندگان
, ,