کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9207911 | 1191760 | 2005 | 4 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
A basic fibroblast growth factor improved the quality of skin grafting in burn patients
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
مراقبت های ویژه و مراقبتهای ویژه پزشکی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: A basic fibroblast growth factor improved the quality of skin grafting in burn patients A basic fibroblast growth factor improved the quality of skin grafting in burn patients](/preview/png/9207911.png)
چکیده انگلیسی
To avoid hypertrophic scars in burn wounds, the simultaneous application of basic fibroblast growth factor (bFGF) with regular surgical debridement and skin grafting was investigated for skin hardness by clinical examination and instrumental measurement. As little is known about the role of bFGF in wounds, burn wound scars were tested for hardness. Burn scars in various anatomical locations at least 1 year after final wound healing clinically demonstrated a significantly lower hard score in bFGF-treated wounds than in non-bFGF wounds (0.95 ± 0.51 versus 2.3 ± 0.66, respectively, p < 0.01). In addition, a durometer, which is widely used in industry to measure materials similar to skin, such as rubber and thread-balls, demonstrated a significantly lower reading in bFGF-treated wounds than in non-bFGF wounds (7.9 ± 3.64 versus 15.5 ± 4.39, bFGF versus non-bFGF, respectively, p < 0.01). The results demonstrated that burn wounds treated with clinically approved bFGF might contribute to a better cutaneous wound quality, at least in terms of hardness.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Burns - Volume 31, Issue 7, November 2005, Pages 855-858
Journal: Burns - Volume 31, Issue 7, November 2005, Pages 855-858
نویسندگان
Sadanori Akita, Kozo Akino, Toshifumi Imaizumi, Akiyoshi Hirano,