کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
925376 921486 2013 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Early gray-matter and white-matter concentration in infancy predict later language skills: A whole brain voxel-based morphometry study
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Early gray-matter and white-matter concentration in infancy predict later language skills: A whole brain voxel-based morphometry study
چکیده انگلیسی

Magnetic Resonance Imaging (MRI) brain scans were obtained from 19 infants at 7 months. Expressive and receptive language performance was assessed at 12 months. Voxel-based morphometry (VBM) identified brain regions where gray-matter and white-matter concentrations at 7 months correlated significantly with children’s language scores at 12 months. Early gray-matter concentration in the right cerebellum, early white-matter concentration in the right cerebellum, and early white-matter concentration in the left posterior limb of the internal capsule (PLIC)/cerebral peduncle were positively and strongly associated with infants’ receptive language ability at 12 months. Early gray-matter concentration in the right hippocampus was positively and strongly correlated with infants’ expressive language ability at 12 months. Our results suggest that the cerebellum, PLIC/cerebral peduncle, and the hippocampus may be associated with early language development. Potential links between these structural predictors and infants’ linguistic functions are discussed.


► VBM identified links between brain anatomy at 7 m and language skills at 12 m.
► WM concentration in the cerebellum and PLIC correlated with receptive language.
► GM concentration in the cerebellum correlated with receptive language.
► GM concentration in the hippocampus correlated with expressive language.
► The cerebellum, hippocampus, and PLIC may contribute to early language development.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Language - Volume 124, Issue 1, January 2013, Pages 34–44
نویسندگان
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