کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
925529 1474053 2011 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Mechanisms of aphasia recovery after stroke and the role of noninvasive brain stimulation
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی روانپزشکی بیولوژیکی
پیش نمایش صفحه اول مقاله
Mechanisms of aphasia recovery after stroke and the role of noninvasive brain stimulation
چکیده انگلیسی

One of the most frequent symptoms of unilateral stroke is aphasia, the impairment or loss of language functions. Over the past few years, behavioral and neuroimaging studies have shown that rehabilitation interventions can promote neuroplastic changes in aphasic patients that may be associated with the improvement of language functions. Following left hemisphere strokes, the functional reorganization of language in aphasic patients has been proposed to involve both intrahemispheric interactions between damaged left hemisphere and perilesional sites and transcallosal interhemispheric interactions between the lesioned left hemisphere language areas and homotopic regions in the right hemisphere. A growing body of evidence for such reorganization comes from studies using transcranial magnetic stimulation (TMS) and transcranial direct current stimulation (tDCS), two safe and noninvasive procedures that can be applied clinically to modulate cortical excitability during post-stroke language recovery. We discuss a hierarchical model for the plastic changes in language representation that occur in the setting of dominant hemisphere stroke and aphasia. We further argue that TMS and tDCS are potentially promising tools for enhancing functional recovery of language and for further elucidating mechanisms of plasticity in patients with aphasia.


► Multiple mechanisms contribute to recovery in patients with post-stroke aphasia.
► Changes include reorganization of the lesioned left and intact right hemispheres.
► Noninvasive brain stimulation may allow for enhancement of language recovery.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain and Language - Volume 118, Issues 1–2, July 2011, Pages 40–50
نویسندگان
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