کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9263326 | 1216028 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Imipenem-resistant Achromobacter xylosoxidans carrying blaVIM-2-containing class 1 integron
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موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Imipenem-resistant Achromobacter xylosoxidans carrying blaVIM-2-containing class 1 integron Imipenem-resistant Achromobacter xylosoxidans carrying blaVIM-2-containing class 1 integron](/preview/png/9263326.png)
چکیده انگلیسی
We characterized seven isolates of imipenem-resistant Achromobacter xylosoxidans that were isolated from patients hospitalized in the intensive care unit at a tertiary hospital in Korea during 2001 to 2003. From the analysis with an isoelectric focusing, polymerase chain reaction, and sequencing methods, all isolates were found to produce VIM-2, OXA-30, and chromosomal AmpC β-lactamase with a pI of 8.4. They showed a similar antibiogram, which were resistant to all tested aminoglycosides as well as β-lactams including imipenem (16-32 mg/L) and aztreonam (128 mg/L), and a same DNA fingerprinting pattern by random amplified polymorphic DNA analysis, suggesting that these originated from a single clone. From the analysis of integron structure carried by an isolate of A. xylosoxidans CBU1760, blaVIM-2 was found to be part of a gene cassette carried on a class 1 integron (3.4 kb) containing three aacA4 gene cassettes. This is the first report of blaVIM-2 in A. xylosoxidans.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 53, Issue 3, November 2005, Pages 215-220
Journal: Diagnostic Microbiology and Infectious Disease - Volume 53, Issue 3, November 2005, Pages 215-220
نویسندگان
Kyeong Seob Shin, Kyudong Han, Jungnam Lee, Seung Bok Hong, Bo Ra Son, Sei Jin Youn, Jungmin Kim, Hyung Sik Shin,