کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
929771 1474390 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Slowing with end-stage renal disease: Attentive but unprepared to act
ترجمه فارسی عنوان
کاهش بیماری کلیه در مرحله پایانی: توجه، اما عدم آمادگی برای عمل
کلمات کلیدی
پتانسیل مربوط به رویداد (ERPs)؛ بیماری مزمن کلیوی؛ حساسیت توجه؛ عمل قصد؛ انرژی سازی؛ کنترل اجرایی؛ آماده سازی پاسخ
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


• We report findings from dialyzed patients with chronic renal disease & healthy people.
• Certain reaction time & ERP results revealed action preparation deficits in patients.
• These deficits were observed when long but not short action preparation was needed.
• Patients also showed higher reactive mobilization in long action preparation periods.
• There were no perceptual preparation and monitoring deficits in the patients' group.

Dialyzed patients show longer response latencies to stimuli than healthy controls. This study was designed to learn if this abnormal latency may be related to an impairment in the networks that mediate the allocation of sensory-attention (inducing a delay in stimulus recognition-awareness) and/or an impairment of intentional motor preparation (inducing a delay in action-initiation). Dialyzed patients with end-stage renal disease and matched healthy controls were assessed using reaction time tasks from the ROtman-Baycrest Battery to Investigate Attention (ROBBIA) and event-related potentials (ERPs) to help elucidate the possible attentional and/or intentional brain mechanisms that may account for this slowing. The following ERP components were analyzed for single attentional and intentional processes: response preparation (Contingent Negative Variation); perceptual preparation (P1); selective attention and monitoring (P300/Late Positive Potential). Patients (vs. controls) had a decreased ability to sustain response preparation under the condition of a long (3 s) but not a short (1 s) preparation period. This action-intentional deficit was, however, not accompanied by impaired perceptual preparation and monitoring. Future research may investigate whether deficits observed in dialyzed patients can be reduced with treatments such as kidney transplantation.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Psychophysiology - Volume 106, August 2016, Pages 30–38
نویسندگان
, , , , , , ,