کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9319139 | 1599487 | 2005 | 14 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Molecular Diagnostics in Prostate Cancer
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
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چکیده انگلیسی
Since there are no effective therapeutic options for advanced prostate cancer, early detection of this tumour is pivotal and can increase the curative success rate. Although the routine use of serum PSA testing has undoubtedly increased prostate cancer detection, one of its main drawbacks has been the lack of specificity that results in a high negative biopsy rate. Since prostate cancer is a heterogeneous disease, it has become clear that a defined set of markers will provide significantly more diagnostic information than any one biomarker. The list of potential prostate cancer biomarkers will continue to grow. Only when research groups use the proposed guidelines for biomarker development, then systematic evaluation and clinical investigation of these biomarkers will gain more insight into their true diagnostic potential.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: EAU Update Series - Volume 3, Issue 4, December 2005, Pages 200-213
Journal: EAU Update Series - Volume 3, Issue 4, December 2005, Pages 200-213
نویسندگان
Daphne Hessels, Harry G. Rittenhouse, Jack A. Schalken,