کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9323487 | 1253608 | 2005 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
An update: spontaneous premature ovarian failure is not an early menopause
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کلمات کلیدی
Fmr1Autoimmune oophoritishypergonadotropic amenorrhea - آمنوره هیپرگونادوتروپیکEstrogen - استروژنhormone replacement - جایگزینی هورمونfragile X syndrome - سندرم X شکننده Ovarian insufficiency - نارسایی تخمدانpremature ovarian failure - نارسایی زودرس تخمدانAdrenal insufficiency - نارسایی قلبی عروقیHypothyroidism - کم کاری تیروئیدPremature menopause - یائسگی زودرس
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: An update: spontaneous premature ovarian failure is not an early menopause An update: spontaneous premature ovarian failure is not an early menopause](/preview/png/9323487.png)
چکیده انگلیسی
Clearly the ovarian “failure” in this disorder is not permanent in all women. Approximately 5%-10% may conceive spontaneously and unexpectedly after the diagnosis. An integrated approach to management is best, and there is a need to first address physical and mental health issues before addressing plans for family building. Women with spontaneous POF are at increased risk of adrenal insufficiency, which should be detected and managed appropriately, especially before proceeding to ovum or embryo donation procedures. Young women with POF experience pathologically low serum E2 levels at least intermittently. Despite the absence of controlled evidence for this specific population, physiologic replacement of ovarian steroid hormones seems rational until the age of normal menopause. The disorder may be associated with other conditions that require evaluation and management, including hypothyroidism, dry eye syndrome, abnormal karyotype, or a premutation of the FMR1 gene. Finally, clinicians need to be sensitive to the emotional aspects of this disorder when delivering the diagnosis and during subsequent management.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Fertility and Sterility - Volume 83, Issue 5, May 2005, Pages 1327-1332
Journal: Fertility and Sterility - Volume 83, Issue 5, May 2005, Pages 1327-1332
نویسندگان
Lawrence M. M.D., Sharon N. L.C.S.W.-C., Robert W. M.D.,