کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9335223 | 1256873 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
FISH screening of aneuploidies in preimplantation embryos to improve IVF outcome
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
زنان، زایمان و بهداشت زنان
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چکیده انگلیسی
Preimplantation genetic diagnosis (PGD) has transformed the approach to the infertility patient in the IVF setting. Although the principal applications of PGD have been to prevent the transmission of sex-linked diseases, in time and with growing knowledge of the chromosomal abnormalities observed in preimplantation embryos, its applications have widened. Nowadays, apart from its implications in the prevention of transmission of chromosomal and genetic abnormalities, PGD is being used with increased frequency to improve the IVF outcome in patients with advanced maternal age (â¥38 years of age), recurrent miscarriage (â¥2 miscarriages), recurrent IVF failure (â¥3 failed IVF attempts) and severe male infertility. A high incidence of chromosomal abnormalities has been observed in these patient groups.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Reproductive BioMedicine Online - Volume 11, Issue 4, 2005, Pages 497-506
Journal: Reproductive BioMedicine Online - Volume 11, Issue 4, 2005, Pages 497-506
نویسندگان
Carmen Rubio, Lorena Rodrigo, Inmaculada Pérez-Cano, Amparo Mercader, Emilia Mateu, Pilar BuendÃa, José RemohÃ, Carlos Simón, Antonio Pellicer,