کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9348500 | 1263575 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
The optomotor response: A robust first-line visual screening method for mice
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موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
سیستم های حسی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: The optomotor response: A robust first-line visual screening method for mice The optomotor response: A robust first-line visual screening method for mice](/preview/png/9348500.png)
چکیده انگلیسی
In both scotopic and photopic conditions, the rotation of a grating was found to elicit head movements in mice. The highest spatial frequency eliciting this optomotor response provided an estimate of visual acuity. In male C57BL/6J mice, visual acuity increased from 0.26Â cpd in scotopic conditions to 0.52Â cpd in photopic conditions whereas it was 0.52Â cpd in both sets of conditions in 129/SvPas mice. No optomotor response was detected in albino CD1 mice and rd1 retinal degeneration mice although light sensitivity in CD1 mice was attested by photophobia and normal electroretinograms. This rapid and cheap method could provide a powerful test of visual performance in genetically modified and pharmacologically treated mice.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Vision Research - Volume 45, Issue 11, May 2005, Pages 1439-1446
Journal: Vision Research - Volume 45, Issue 11, May 2005, Pages 1439-1446
نویسندگان
Jellali Abdeljalil, Meziane Hamid, Ouagazzal Abdel-mouttalib, Rousseau Stéphane, Romand Raymond, Auwerx Johan, Sahel José, Chambon Pierre, Picaud Serge,