کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
936552 1475162 2014 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Stressor controllability modulates fear extinction in humans
ترجمه فارسی عنوان
کنترل پذیری استرس موجب انقراض ترس در انسان می شود
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی

Traumatic events are proposed to play a role in the development of anxiety disorders, however not all individuals exposed to extreme stress experience a pathological increase in fear. Recent studies in animal models suggest that the degree to which one is able to control an aversive experience is a critical factor determining its behavioral consequences. In this study, we examined whether stressor controllability modulates subsequent conditioned fear expression in humans. Participants were randomly assigned to an escapable stressor condition, a yoked inescapable stressor condition, or a control condition involving no stress exposure. One week later, all participants underwent fear conditioning, fear extinction, and a test of extinction retrieval the following day. Participants exposed to inescapable stress showed impaired fear extinction learning and increased fear expression the following day. In contrast, escapable stress improved fear extinction and prevented the spontaneous recovery of fear. Consistent with the bidirectional controllability effects previously reported in animal models, these results suggest that one’s degree of control over aversive experiences may be an important factor influencing the development of psychological resilience or vulnerability in humans.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 113, September 2014, Pages 149–156
نویسندگان
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