کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
936597 1475169 2013 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of the dorsal dentate gyrus in object and object-context recognition
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
پیش نمایش صفحه اول مقاله
The role of the dorsal dentate gyrus in object and object-context recognition
چکیده انگلیسی


• The dorsal dentate gyrus plays an important role in object-context recognition at short retention intervals.
• The dorsal dentate gyrus does not play a role in object recognition at short retention intervals.
• The dorsal dentate gyrus plays an important role in object recognition at long retention intervals.

The aim of this study was to determine the role of the dorsal dentate gyrus (dDG) in object recognition memory using a black box and object-context recognition memory using a clear box with available cues that define a spatial context. Based on a 10 min retention interval between the study phase and the test phase, the results indicated that dDG lesioned rats are impaired when compared to controls in the object-context recognition test in the clear box. However, there were no reliable differences between the dDG lesioned rats and the control group for the object recognition test in the black box. Even though the dDG lesioned rats were more active in object exploration, the habituation gradients did not differ. These results suggest that the dentate gyrus lesioned rats are clearly impaired when there is an important contribution of context. Furthermore, based on a 24 h retention interval in the black box the dDG lesioned rats were impaired compared to controls.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Learning and Memory - Volume 106, November 2013, Pages 112–117
نویسندگان
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