The neural basis of aberrant speech and audition in autism spectrum disorders

Autism spectrum disorders (ASD) are characterized by deficits in communication and social behavior and by narrow interests. Individuals belonging to this spectrum have abnormalities in various aspects of language, ranging from semantic-pragmatic deficits to the absence of speech. They also have aberrant perception, especially in the auditory domain, with both hypo- and hypersensitive features. Neurophysiological approaches with high temporal resolution have given novel insight into the processes underlying perception and language in ASD. Neurophysiological recordings, which are feasible for investigating infants and individuals with no speech, have shown that the representation of and attention to language has an abnormal developmental path in ASD. Even the basic mechanisms for fluent speech perception are degraded at a low level of neural speech analysis. Furthermore, neural correlates of perception and some traits typical of subgroups of individuals on this spectrum have helped in understanding the diversity on this spectrum.

► Both hypo- and hypersensitive neural reactivity to sounds in autism spectrum.
► Orienting to speech is impaired in autism since infancy.
► Impaired neural sound invariance detection may underlie speech perception deficits.
► Neural correlates associated with traits illuminate diversity of autism spectrum.