کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9401477 | 1288264 | 2005 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Prognostic factors and evaluation of surgical management of hepatic metastases from colorectal origin: a 10-year single-institute experience
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
عمل جراحی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
The aim of this study was to determine prognostic factors and outcome after liver resection for colorectal metastases in 102 patients over a period of 10 years. A stepwise procedure using proportional hazard regression analysis was used to identify prognostic factors. Estimated survival at 2 years was 71%, and at 5 years, 29% (Kaplan-Meier). Of 19 patients with isolated liver recurrence, 6 had a second metastasectomy; 4 of the 6 are still alive. We found that the number of hepatic lesions on computed tomography (PÂ =Â 0.012), the interval between resection of the primary colon tumor and the hepatic metastasectomy (PÂ =Â 0.012), and synchronicity of the primary and the hepatic metastasis (PÂ =Â 0.048) showed evidence of independent prognostic value regarding survival. Resection of hepatic colorectal metastases may result in long-term survival. Patients with recurrence after a first liver resection may benefit from a repeat metastasectomy. Our data suggest there is no strong predictor of survival. Survival seems to decrease with increasing number of metastases found on computed tomography.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Gastrointestinal Surgery - Volume 9, Issue 2, 1 February 2005, Pages 178-186
Journal: Journal of Gastrointestinal Surgery - Volume 9, Issue 2, 1 February 2005, Pages 178-186
نویسندگان
Eduard L.A.R. M.D., Ph.D., Serge M.D., Ph.D., Frans A.N. M.D., Ph.D., Emiel J.T. M.D., Ph.D., F.R.C.S., Augustinus A.M. Ph.D., Frits M.D., Ph.D.,