کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9401488 | 1288264 | 2005 | 10 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Hypercalcemia and pancreatic endocrine neoplasia with elevated PTH-rP: report of two new cases and subject review
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
عمل جراحی
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Hypercalcemia and pancreatic endocrine neoplasia with elevated PTH-rP: report of two new cases and subject review Hypercalcemia and pancreatic endocrine neoplasia with elevated PTH-rP: report of two new cases and subject review](/preview/png/9401488.png)
چکیده انگلیسی
Humoral hypercalcemia of malignancy is widely associated with tumor production of parathyroid hormone related protein (PTH-rP). This peptide functions in endocrine, autocrine and paracrine mechanisms in a manner similar to PTH; increasing renal uptake of calcium, decreasing retention of phosphorous, and stimulating adenylate cyclase and phospholipase C. Although PTH-rP production has been well documented in neoplasms of the exocrine pancreas, we present here two cases of endocrine pancreatic neoplasms elaborating PTH-rP. We then review the literature of previous cases and delve into the pathophysiology of this peptide.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Gastrointestinal Surgery - Volume 9, Issue 2, 1 February 2005, Pages 270-279
Journal: Journal of Gastrointestinal Surgery - Volume 9, Issue 2, 1 February 2005, Pages 270-279
نویسندگان
Susanna L. M.D., Charles J. M.D., Ralph H. M.D., Michael A. M.D.,