Effects of Ischemic Preconditioning on Regenerative Capacity of Hepatocyte in the Ischemically Damaged Rat Livers

These results suggest that ischemic pre-conditioning ameliorates the hepatic injury associated with ischemia-reperfusion and has a stimulatory effect on liver cell regeneration that may make it valuable as a hepatoprotective modality. Il-6 appears to be key mediator in promoting regeneration after combined ischemia and hepatic resection.