کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9422682 | 1614465 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures Electron spin resonance assay of ascorbyl radical generation in mouse hippocampal slices during and after kainate-induced seizures](/preview/png/9422682.png)
چکیده انگلیسی
As an index of oxidative status, we analyzed ascorbyl radical generation during and after kainate-induced seizures in mouse hippocampus, using an ESR spectrometer equipped with a special tissue-type quartz cell. A specific doublet ESR spectrum was observed after seizures, and the g value and the hyperfine coupling constant (hfcc) of the spectrum were identical with those of ascorbyl radical itself. Antiepileptic zonisamide inhibited the generation of ascorbyl radical accompanying the seizures.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Brain Research Protocols - Volume 16, Issues 1â3, December 2005, Pages 65-69
Journal: Brain Research Protocols - Volume 16, Issues 1â3, December 2005, Pages 65-69
نویسندگان
Toshiki Masumizu, Yasuko Noda, Akitane Mori, Lester Packer,