کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9429537 | 1297048 | 2005 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Aversive effects elicited by electrical stimulation of the inferior colliculus in normal and audiogenic seizure susceptible rats
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Aversive effects elicited by electrical stimulation of the inferior colliculus in normal and audiogenic seizure susceptible rats Aversive effects elicited by electrical stimulation of the inferior colliculus in normal and audiogenic seizure susceptible rats](/preview/png/9429537.png)
چکیده انگلیسی
Trains of electrical stimulations were applied to the dorsal or ventral part of the inferior colliculus (IC) of audiogenic seizure susceptible rats from the AGSR strain. Threshold and duration of wild running (WR), were evaluated in the first experiment. All stimulation sites elicited WR, even in normal control rats. Stimulation of the IC of AGSR rats required a lower quantity of current, i.e., such brain sites were more sensitive to the current, than normal controls. The duration of post-stimulus WR was shorter in AGSR rats. Lower quantities of current applied to the ventral IC were needed to elicit WR than to the dorsal IC in AGSR rats. In a second experiment, using the same stimulations sites in the same rats, the emotional effect of the stimulation was tested through an instrumental learning procedure (switch-off paradigm) in which the rat was trained to press a bar to put an end to the stimulation. Both dorsal and ventral IC stimulation sites sustained switch-off behavior in AGSR rats, but only ventral IC stimulation sites sustained switch-off learning in control rats.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Letters - Volume 379, Issue 3, 13 May 2005, Pages 180-184
Journal: Neuroscience Letters - Volume 379, Issue 3, 13 May 2005, Pages 180-184
نویسندگان
Abdallah Bagri, Guy Sandner, Georges Di Scala,