کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9434495 | 1298157 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
علم عصب شناسی
علوم اعصاب (عمومی)
پیش نمایش صفحه اول مقاله
![عکس صفحه اول مقاله: Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice Altered food-anticipatory activity rhythm in Cryptochrome-deficient mice](/preview/png/9434495.png)
چکیده انگلیسی
In this study, we investigated the impact of the absence of mCRY products upon the locomotion pattern induced by RF. RF caused an increase in daytime activity that lasted even for 2 days after food was withheld, in wild-type and mCry1â/â mCry2â/â mice. However, RF-induced activity was less stable and appeared more gradually in mutant mice. Similar results were obtained with mice housed under constant darkness or with SCN-lesioned wild-type and mutant mice. Our data reveal that mCry proteins are basically dispensable for food-entrainable oscillation. However, it is also important to note that mCry deficiency affects the stability and development of RF-induced anticipatory locomotor activity.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Research - Volume 52, Issue 2, June 2005, Pages 166-173
Journal: Neuroscience Research - Volume 52, Issue 2, June 2005, Pages 166-173
نویسندگان
Michihiko Iijima, Shun Yamaguchi, Gijsbertus T.J. van der Horst, Xavier Bonnefont, Hitoshi Okamura, Shigenobu Shibata,