کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
9728006 | 1480215 | 2005 | 8 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Topological effects of fitness landscapes on the process of fixation of advantageous mutations
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کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
ریاضیات
فیزیک ریاضی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
We investigate the dependence of the dynamics of fixation of advantageous mutations on the topology of fitness landscapes. We study the problem by means of a simple model of fitness landscape at which we tune the degree of correlation between related sequences by changing the correlation parameter λ. We observe the existence of two evolutionary regimes: one for small to intermediate values of selective effect of beneficial mutations s, and another for high values of s. In the former, the likelihood of ultimate fixation of advantageous mutations, when we consider uncorrelated or low correlated fitness landscapes is greater than that for highly correlated fitness landscapes when compared to the low correlated case. In the second regime, we obtain an opposed behavior and now the probability of fixation is higher for highly correlated fitness landscapes when, compared to the low correlated case.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Physica A: Statistical Mechanics and its Applications - Volume 346, Issues 3â4, 15 February 2005, Pages 451-458
Journal: Physica A: Statistical Mechanics and its Applications - Volume 346, Issues 3â4, 15 February 2005, Pages 451-458
نویسندگان
Viviane M. de Oliveira, Paulo R.A. Campos,