کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
975003 | 1480146 | 2015 | 7 صفحه PDF | دانلود رایگان |

• The role of extrinsic periodic information on intracellular calcium oscillation is studied.
• Extrinsic periodic information interpolates synchronous and anti-synchronous oscillation.
• Extrinsic periodic information interpolates bistable and monostable states of intracellular calcium oscillation.
Extrinsic periodic information including physiological cyclical and circadian replacement would affect inevitably a real cell, in this paper we investigate the effect of extrinsic periodic information on intracellular calcium dynamics by means of second-order algorithm for stochastic simulation colored noises. By simulating time evolutions and stationary probability distribution of intracellular Ca2+ concentrations, the results show: (i) intracellular calcium oscillation between cytosol and calcium store shows synchronous and anti-synchronous oscillation as intensity and frequency of extrinsic periodic information vary; (ii) extrinsic periodic information interpolates stability from bistable state →→ monostable state →→ bistable state →→ monostable state as frequency of extrinsic periodic information increases; (iii) extrinsic periodic information interpolates stability from monostable state →→ bistable state as intensity of extrinsic periodic information increases.
Journal: Physica A: Statistical Mechanics and its Applications - Volume 427, 1 June 2015, Pages 155–161