Modeling cancer immunotherapy: Assessing the effects of lymphocytes on cancer cell growth and motility

► We develop a spatio-temporal model for the tumor-lymphocytes interaction. ► We examine the effect of immunotherapeutic action. ► Chemotactic lymphocyte guidance is shown to play a minor role. ► Lymphocyte blockade of advancing tumor cells effectively helps control growth. ► Results suggest the inclusion of an anti-migratory agent in a therapeutic program.